The way things are going, if it happens, will be based on religion

Religion alone can't cause war or destruction.

Like which one(s)?

Religion is actually that glue that holds the world together. Imagine USA without religion. They would have long annihiltated us and occupied our continent. Those of us, who live in Europe know that it is only Christianity that prevents these guys from putting us in a gas chamber. For those married to local women here, they know that is only because of Christianity that the girls' fathers have not put a knife on their throats

It will most likely be about resources (read oil) and other metals. Will have noting to do with religion

Forgive (some) ignorance when you find it.

If you go back to history far enough, there was a major war almost every time there was shift in military and economic dominance from one power to another ...indeed, it is these wars that were ultimate judges who's the greater power...since humans are animals, perhaps if you can project far into the future when some other economy will be twice that of US in size, and since military power and economy go hand in hand, possibility of major conflict will be real....but before that there will be many wars on twitter ...

The way I see it, religion is hardly the issue here. Many of the world's wars have been waged by the global elite, using their goons and militia, but using a religious pretext. Look at IS for example, there is evidence going around that this is actually a CIA-backed operation (though on the surface it may appear to be members of a certain religion going for the necks of "non-believers", as they call them.) The same case applies in the Israeli-Palestinian conflict, where the aggressor has been known to mercilessly carry out false-flag attacks against its own people and use them as an excuse to carry out retaliatory attacks against the perceived 'enemies'. Its kind of how politicians here at home hide behind "my tribe", and every so often they chime out some insult against rival tribes that charges people and causes a lot of intolerant comments (especially on social media.) The end result is war/conflict, and guess who rejoices at the spoils of war?

Don't you just love it how they began with the Shah, then Saddam, then Osama, then the Taliban and now ISIS? They buried Osama in the ocean because they actually cared for his religious beliefs?? Come on now.