Especially when they follow each other in one sentence
"... it's not you it's me..."
"... let's just be friends."
"In my humble opinion..." when the person uttering the words almost always means " you stupid bufoon" and their opinion is wrong 80% of the time.
Would also not like to be on the receiving end of this one which is heavily loaded with meaning
"When I need you opinion I will flush a toilet"
"We do not inherit the earth from our ancestors, we borrow it from our children" Native American Proverb