sentinel prime wrote:did you know the europeans who survived the plague passed on the genes to their descendants and are immune to hiv?
Very true
https://www.eeb.ucla.edu...iNovembreMicInf2005.pdf
"Although the origin of the mutation is obscure, it appears to have suddenly become relatively common among white Europeans about 700 years ago. That increase suggests that something must have occurred about that time to greatly favor the survival of people carrying the mutation."
What biological catastrophe decimated Europe 700 years ago? The Black Death. One-quarter to one-third of the Europeans succumbed between 1347 and 1350. The Black Death strongly modified the European gene pool, increasing the frequency of CCR5-delta 32. This mutation may not have had any direct effect on the plague itself. It may just be a quirk of fate that the survivors of the Black Death had a higher frequency of the CCR5-delta 32 mutation, and it is doubly quirky that the mutation confers a resistance to AIDS, which is a recent human affliction.
About 10% of whites of European origin now carry the CCR5-delta 32 mutation. The incidence is only 2% in central Asia. The mutation is completely absent among East Asians, Africans, and American Indians.
However, i also have to say that CXCR4 utilizing strains can still infect patients despite CCR5 mutations. Subtype D prevalent in Kenya utilizes CXCR4 frequently.
Do you also know that African will also be the first to adapt to living with the HIV? My studies on subtype C are pointing to that direction. Infact the reason why subtype C has spread so fast is because this subtype is less aggressive in vitro and in vivo and is able to propagate further due to invisibility. This are some of the lessons we learn when we compare HIV-1 and HIV-2 via epidemiological studies.
History will not remember you for your IQ. It will remember you for what you did. “Genius is 1 percent inspiration, 99 percent perspiration.” Thomas Edison